AB0934
HIGHER DISEASE ACTIVITY AND EARLIER ARTHRITIS ONSET ARE ASSOCIATED WITH RISK OF CORONARY HEART DISEASE DEVELOPMENT IN PATIENTS WITH PSORIATIC ARTHRITIS
I. Gaydukova 1,*A. Rebrov 1D. Poddubnyy 1
1Hospital Therapy, Saratov Medical State University Of Roszdrav, Saratov, Russian Federation
Background: Psoriatic arthritis (PsA) is characterized by increased cardiovascular morbidity and mortality [1]. However, data about clinical features of PsA related to adverse cardiovascular events in this population are limited.
Objectives: The aim of the study was to evaluate disease related factors associated with coronary heart disease’s (CHD) manifestation in patients with PsA.
Methods: 52 patients with PsA according to CASPAR criteria without clinical features of cardiovascular diseases were involved in the study. Screening for cardiovascular risk factors and cardiovascular disease was performed at baseline and after 6 to 12 month of observation. PsA activity assessment was performed by standard procedures (disease activity score (DAS), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP)).
Results:
Conclusions: Higher activity of PsA, earlier disease onset and, consequently, longer disease duration associates with an exceeded risk of CHD in PsA patients independently from convectional cardiovascular risk factors.
References: 1. Gladman DD, et al. Arthritis Rheum 1998;41:1103-10.
Disclosure of Interest: None Declared