ESPEN 2012 - Late breaking abstract submission

Topic: Late Breaking Abstract

Abs n°:ESPEN12-1877

Abs Title: EFFECTS OF SWEET SUBSTANCE DEPENDENCE (SSD) IN PLASMA LEVELS OF LEPTIN IN WOMEN

D. M. Macedo ^1,*R. W. Diez-Garcia ¹A. A. Jordão Júnior ¹

¹Department of Clinical Medicine, Faculty of Medicine of Ribeirao Preto, University of São Paulo / USP, Ribeirão Preto, Brazil

Rationale: Introduction: The SSD and high levels of leptin seem to further activate the mesolimbic brain region. Objective: To characterize the SSD and compare the plasma levels of leptin between women with and without SSD.

Methods: The SSD was identified through the "You have felt a strong desire to eat sweet in the last three months?¹" and the sample was divided into two groups (with and without SSD). We used the "Questionnaire for Assessing Abuse and Dependence Sugar²" to characterize the SSD, and qualitative questions to map the consumption of sugars. The baseline plasma levels of leptin were measured and compared between groups.

Results: Fifty-seven women participated in the study, 32 with SSD (56,14%) and 25 without SSD (43,86%). Comparing women with and without SSD, the most women with SSD using the candy to improve mood (p<0,01), increasing amounts to feel good (p<0,01), feel symptoms in the absence of sweets (p<0,01), eat more sweets than intended (p<0,01), they had tried but failed to stop or reduce the consumption of sweets; spend hours thinking about how to acquire them (p<0,01); they have stopped doing any activity to be eating sweets (p<0,01); and still eating these foods even though it can cause problems (p<0,01). The variety, the amount of sweets, and eating behaviors observed were different between the groups. The mean plasma levels of leptin was significantly higher among women with SSD (p<0,01).

Conclusion: Women with SSD showed peculiar behavior related to the search for sweets and increased plasma levels of leptin.

Reference(s): ¹WEINGARTEN H. P.; ELSTON, C. Food cravings in a college population. Appetite, London, v. 17, n. 3, p. 167-175, 1991.

²ROSA, M. A. C.; SLAVUTZKY, S. M. B.; PECHANSKY, F.; KESSLER, F. Processo de desenvolvimento de um questionário para avaliação de abuso e dependência de açúcar. Caderno de Saúde Pública, Rio de Janeiro, v. 24, n. 8, p. 1869-1876, 2008.

Disclosure of Interest: None Declared

Keywords: LEPTINSWEET SUBSTANCE DEPENDENCE (SSD)