ESPEN 2012 - Late breaking abstract submission

Topic: Late Breaking Abstract

Abs n°:ESPEN12-1887

Abs Title: EVALUATION OF MAGNESIUM DEFICIENCY IN THE CZECH POPULATION AND THE INFLUENCE OF SUPPLEMENTATION BY MAGNESIUM-RICH MINERAL WATER

R. Hyspler ^1,*A. Ticha ¹I. Svobodova ¹J. Pavlickova ¹Z. Zadak ¹R. Soukupova ²

¹Dept. of Gerontology and Metabolism, UNIVERSITY HOSPITAL HRADEC KRALOVE, Hradec Kralove, ²Karlovarske mineralni vody, a.s., Praha, Czech Republic

Rationale: The aim of this study was to quantify the risk of  magnesium deficinecy in our population by questionnaire and to evaluate the effect of supplementation by mineral water rich in magnesium.

Methods: Out-patients and healthy personnel (n=100) mean age  43 ± 20.7 years were investigated by adjusted magnesium deficiency questionnaire and urine magnesium was determined. Fifty patients were randomly selected from this group for plasma magnesium determination before and after 3 weeks;  25 patients  received supplementation by mineral water reach in magnesium was performed in (Magnesia, Carlsbad mineral waters, 1.5 l [270 mg Mg]) daily for 3 weeks. Plasma and urine magnesium were determined by enzymatic methods (Dialab, CZ). The data were statistically analyzed by software SigmaStat – Pearson´s correlation adn t-test. Data are prezented as mean ± standard deviation.

Results: The questionnaire indicated probable magnesium deficit in 25 % of all patients, and almost certain magnesium deficit in 4 % of patients. The recorded scores correlated positively with age of patients (P=0.003) and negatively with urine magnesium (P<0.001). Plasma magnesium was compared in groups with and without supplementation (Magnesia and control group, respectively) before and after 3 weeks of investigation (Magnesia group before:  0.814 ± 0.08 mmol/l,  Magnesia after 3 weeks 0.977 ± 0.15 mmol/l, P<0.001, controls before 0.87 ± 0.16; controls after 3 weeks 0.94 ± 0.15,  ns.).

Conclusion: Risk of magnesium deficiency was found in 29 % patients by adjusted questionnaire. The questionnaire scores significantly correlated with age and magnesium concentration in urine. The significant elevation of plasma magnesium concentration indicates good bioavailability of magnesium in tested mineral water.

Supported by grant IGA MZ CR NT/13536-4/12.

Disclosure of Interest: None Declared

Keywords: magnesium deficiency, mineral water