ESPEN 2012 - Late breaking abstract submission

Topic: Late Breaking Abstract

Abs n°:ESPEN12-1897

Abs Title: ASSOCIATION BETWEEN COFFEE CONSUMPTION AND CHRONIC KIDNEY DISEASE IN KOREAN WOMEN WITH AND WITHOUT DIABETES ; ANALYSIS OF THE FOURTH KOREA NATIONAL HEALTH AND NUTRITION EXAMINATION SURVEY IN 2008

B. H. Kim ^1,*J. K. Lee ¹H.-M. Noh ¹Y. S. Park ²I. H. Kim ¹

¹family medicine, Samsung Medical Center, ²family medicine, Kangbuk Samsung Hospital, Seoul, Korea, Republic Of

Rationale: In previous studies showed coffee consumption has protective effect for development of diabetes by components of coffee act as antioxidants and enhancing insulin sensitivity¹ and also, beneficial effect on cardiovascular disorder by inverse association with markers of inflammation and endothelial dysfunction in American diabetic women² . The aim of this study is to investigate the relationship between habitual coffee consumption and CKD in Korean women.

Methods: This study involved 2,673 women aged 35 to 64 years in the Fourth Korea National Health and Nutrition Examination Surveys conducted in 2008. Habitual coffee consumption classified into three categories; less than 1 cup per day, 1 cup per day, and 2 or more cups per day. CKD was defined as estimated glomerular filtration rate (eGFR) less than 60 ml/min/1.73m² by MDRD equation.

Results: Compared with drinking less than 1 cup of coffee per day, the odds ratio (OR) for CKD was 0.586 (confidence interval [CI], 0.367-0.937; P = 0.026) of habitual drinking 2 or more cups per day after adjusting for multiple confounding factors. In women with diabetes, those with habitual drinking 2 or more cups of coffee per day had significantly lower risk of CKD (OR, 0.135; 95% CI, 0.021-0.882; P=0.037) compared with less than 1 cup per day after adjustment, but not among women without diabetes.

Conclusion: In a representative sample of Korean women, habitual coffee consumption of 2 or more cups per day was significantly associated with a decreased risk of CKD compared with less than 1 cup per day, especially in women with diabetes.

Reference(s): 1)Coffee consumption & risk of type 2 diabetes-a systematic review. JAMA 2005. 294(1): p. 97-104. 2)Coffee consumption and markers of inflammation and endothelial dysfunction in healhty and diabetic women. AJCN, 2006 Oct. 84(4): p. 888-93.

Disclosure of Interest: None Declared

Keywords: coffee, chronic kidney disease, diabetes, KNHANES, nutrition