ESPEN 2012 - Late breaking abstract submission
Topic: Late Breaking Abstract
Abs n°:ESPEN12-1904
Abs Title: RELATIONSHIP BETWEEN NUTRITIONAL STATUS, BODY COMPOSITION, STRENGTH AND PHYSICAL PERFORMANCE IN COMMUNITY-LIVING OLDER MEN AND WOMEN WITH MALNUTRITION AND SARCOPENIA.
V. Mustad 1,*A. J. Cruz Jentoft 2D. S. Hustead 1J. T. Cramer 3 and NCT01191125 Investigators
1Scientific Affairs, Abbott, Columbus, United States, 2Servicio de Geriatría, Hospital Universitario Ramon y Cajal, Madrid, Spain, 3Nutrition and Health Sciences, University Nebraska, Lincoln, United States
Rationale: Nutrition has a profound impact on body composition, strength, and function. However, these relationships have not been fully explored in community-living older men and women having both malnutrition and sarcopenia.
Methods: Men (n=125) and women (n=204), mean±SD age 76±6.4 yrs, were recruited from 8 countries across Europe and North America, having malnutrition (Subjective Global Assessment B or C), and EWGSOP-defined sarcopenia (1). Nutritional assessments included energy (kcal) and protein intake (g/kg bwt) by 3 day dietary records, serum 25-OH D3 (D3) and vitamin B12 (B12).
Results: Energy intake was 1971±623 (men) and 1487±546 (women); 34% of subjects had protein intake <0.8 g/kg bwt; 30% had D3 <20 ng/mL and 26% B12 <350 pg/mL. Correlations were observed between protein intake and/or serum vitamin D with body composition, strength, and physical performance (Table).
Variables |
Protein intake (g/kg bwt) |
Serum 25 OH D3 (ng/mL) | ||
|
Pearson Correlation and p value |
r |
p |
r |
p |
|
Total Body Mass (kg) |
-0.28 |
<0.0001 |
-0.01 |
0.87 |
|
Total Fat Mass (kg) |
-0.41 |
<0.0001 |
-0.08 |
0.15 |
|
Handgrip Strength (kg) |
0.16 |
0.005 |
0.11 |
0.04 |
|
Gait speed (m/sec) |
0.12 |
0.03 |
0.14 |
0.01 |
|
Bone Mineral content (g) |
-0.02 |
0.75 |
0.13 |
0.02 |
|
Bone Mineral density (g/cm) |
-0.00 |
0.97 |
0.14 |
0.02 |
Conclusion: Despite a wide distribution in nutritional status in malnourished and sarcopenic older adults, protein intake and vitamin D are insufficient in one third and significantly associated with body composition, muscle strength and/or physical performance. Interventions targeting nutrition-related sarcopenia should build upon these findings, including a complement of protein and vitamin D.
Reference(s): (1) Cruz-Jentoff AJ, Age Ageing 2010;39(4):412-23.
Disclosure of Interest: V. Mustad Shareholder of: Abbott Other: Abbott EmployeeA. Cruz Jentoft Grant/Research Support from: Abbott NutritionD. Hustead Shareholder of: Abbott Other: Abbott EmployeeJ. Cramer Grant/Research Support from: Abbott Consultant for: Abbott Nutrition
Keywords: Malnutrition, sarcopenia