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O001DISCOVERY OF A NOVEL TRANSCRIPTIONAL REGULATOR OF SUSTAINING TLR-MEDIATED INFLAMMATORY RESPONSES Bin Lin, Bhaskar Dutta, Kyu-Seon Oh, Iain Fraser Oral presentation17.10.201609:00Grand Ballroom AImmune regulation of inflammation and cancerScientific Session
O002TRANSGENE EXPRESSION OF INTERLEUKIN-37 IN IL-10KO MICE INHIBITS COLON CARCINOGENSIS Andrea Ringleb, Rahel Schwaiger, Steffeni Mountford, Doris Mayr, Charles A Dinarello, Philip Bufler Oral presentation17.10.201609:45Grand Ballroom AImmune regulation of inflammation and cancerScientific Session
O003EFFECTS OF MYCOBIOTA DYSBIOSIS DURING INTESTINAL INFLAMMATION Irina Leonardi, Agnieszka Stefania Bar, Iliyan Iliev Oral presentation17.10.201611:30Grand Ballroom AThe microbiota and regulation of inflammationScientific Session
O004MICROBIOME-DEPENDENT MODULATION OF MUCOSAL IMMUNITY AT THE OCULAR SURFACE Anthony J St. Leger, Jigarkumar Desai, Rebecca Drummond, Fatimah Almaghrabi, Phyllis Silver, Michail Lionakis, Rachel Caspi Oral presentation17.10.201612:15Grand Ballroom AThe microbiota and regulation of inflammationScientific Session
O005LKB1 HAPLOINSUFFICIENCY IN T CELLS IS SUFFICIENT TO DRIVE THE DEVELOPMENT OF PEUTZ-JEGHERS SYNDROME Maya Chikako Poffenberger, Eric Ma, Bozena Samborska, Said Izreig, Julianna Blagih, Gino Boily, Russell G Jones Oral presentation17.10.201611:30Grand Ballroom B/CCytokine regulation of cellular metabolismScientific Session
O006COMPLEX REGULATION OF TNF EXPRESSION CONTROLLED BY THE 3’ UNTRANSLATED REGION Philippe Bouillet, Derek Lacey Oral presentation17.10.201612:15Grand Ballroom B/CCytokine regulation of cellular metabolismScientific Session
O007LOW-DOSE INTERLEUKIN-2 TREATMENT MODULATES CD4+ T CELL SUBSETS SELECTIVELY IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS Di Yu, Jing He, Xia Zhang, Yunbo Wei, Xiaolin Sun, Yaping Chen, Nan Shen, Eric Morand, Zhanguo Li Oral presentation17.10.201615:30Grand Ballroom ATo the clinic: Emerging therapiesScientific Session
O008TARGETING THE IL-7R PATHWAY IN LEUKEMIA WITH JAK INHIBITORS AND MABS. Scott Durum, julie hixon, emilee senkevitch, sarah cramer, joao barata, scott walsh, wenqing li Oral presentation17.10.201616:15Grand Ballroom ATo the clinic: Emerging therapiesScientific Session
O009INTERFERON-DRIVEN METABOLIC REPROGRAMMING OF HEPATOCYTES Andreas Bergthaler Oral presentation17.10.201615:30Grand Ballroom B/CInterferons: regulators of immunity and inflammationScientific Session
O010IFNAR SIGNALING OF MYELOID CELLS MODULATES VIRAL HEPATITIS BUT NOT KUPFFER CELL REPLENISHMENT Katharina Borst, Theresa Frenz, Julia Spanier, Pia Tegtmeyer, Chintan Chhatbar, Jennifer Skerra, Stefan Lienenklaus, Mario Köster, Sukumar Namineni, Mathias Heikenwälder, Gerd Sutter, Ulrich Kalinke Oral presentation17.10.201616:15Grand Ballroom B/CInterferons: regulators of immunity and inflammationScientific Session
O011A "RHEOSTAT" FUNCTION FOR THE GP130/STAT3 SIGNALING CASCADE FOR GASTROINTESTINAL WOUND-HEALING AND TUMORIGENESIS Matthias Ernst, Tracy Putoczki, Moritz Eissmann, Frederic Masson Oral presentation18.10.201609:00Grand Ballroom AInnate and adaptive immune mechanisms of host defenseScientific Session
O012IL-17RA SIGNALING IN ORAL EPITHELIUM IS NECESSARY AND SUFFICIENT FOR PROTECTION AGAINST OROPHARYNGEAL CANDIDIASIS Sarah Gaffen, Heather Conti, Erin Childs, Satrajit Sinha, Scott Filler, Vincent Bruno, Jay Kolls Oral presentation18.10.201609:45Grand Ballroom AInnate and adaptive immune mechanisms of host defenseScientific Session
O013 IL-17A EXACERBATES PSORIASIFORM DERMATITIS IN A MOUSE MODEL OF HIGH-FAT DIET-INDUCED STEATOHEPATITIS Jean-Claude Lecron, phillippe Vasseur, Laura Serres, Jean-Francois Jegou, Mathilde Pohin, Adriana Delwail, Isabelle Petit-Paris, Pierre Levillain, Laure Favot, Michel Samson, Hans Yssel, Franck Morel, Christine Silvain Oral presentation18.10.201611:30Grand Ballroom ACytokines and metabolic diseasesScientific Session
O014CARDIOTROPHIN-LIKE CYTOKINE (CLCF1) PARTICIPATES IN LIPOPROTEIN COMPLEXES Sarah Pasquin, Salma Chehboun, Agnieszka Dejda, Mukut Sharma, Przemyslaw Sapieha, Catherine Martel, Jean-François Gauchat Oral presentation18.10.201612:15Grand Ballroom ACytokines and metabolic diseasesScientific Session
O015AN ESSENTIAL ROLE FOR EPITHELIAL CELL HISTONE DEACETYLASE 3 IN INTESTINAL HOST DEFENSE Theresa Alenghat Oral presentation18.10.201611:30Grand Ballroom B/CInnate immunity at barrier surfacesScientific Session
O016INTERFERON-LAMBDA CONTROLS THE SPREAD OF RESPIRATORY VIRUSES FROM THE UPPER RESPIRATORY TRACT TO THE LUNGS AND RESTRICTS VIRUS TRANSMISSION IN MICE Peter Staeheli, Jonas Klinkhammer, Daniel Schnepf, Liang Ye, Marilena Schwaderlapp, Dominique Garcin, Tanel Malakoiv Oral presentation18.10.201612:15Grand Ballroom B/CInnate immunity at barrier surfacesScientific Session
O017NEGATIVE REGULATION OF INNATE IMMUNE SIGNALING BY THE RNA SENSOR, LGP2 Curt Horvath Oral presentation18.10.201615:30Grand Ballroom AThe JICR/Mary Ann Liebert, Inc. Symposium in honor of Philip I. MarcusScientific Session
O018LOSS OF AUTOPHAGY DRIVES INFLAMMATION VIA TYPE I INTERFERONS Mohammad Samie, Joshua Baughman, Ivan Peng, Summer Park, Ning Chai, Min Xu, Brent Mckenzie, Donald Kirkpatrick, Menno van Lookeren Campagne, Aditya Murthy Oral presentation18.10.201616:15Grand Ballroom AThe JICR/Mary Ann Liebert, Inc. Symposium in honor of Philip I. MarcusScientific Session
O019INTERFERON-INDUCIBLE PROTEINS ARE ESSENTIAL FOR THE ACTIVATION OF THE INFLAMMASOMES Si Ming Man, Rajendra Karki, Thirumala-Devi Kanneganti Oral presentation18.10.201616:30Grand Ballroom AThe JICR/Mary Ann Liebert, Inc. Symposium in honor of Philip I. MarcusScientific Session
O020THE LAB ENVIRONMENT RECAPITULATES PRIMARY HUMAN IMMUNE RESPONSES IN MICE Waleed Elsegeiny, Taylor Eddens, Mingqaun Zheng, Jay Kolls Oral presentation18.10.201615:30Grand Ballroom B/CPrimary immunodeficiencies: lessons for cytokine and interferon biologyScientific Session
O021FAMILIAL AUTOINFLAMMATION WITH NEUTROPHILIC DERMATOSIS REVEALS A NOVEL REGULATORY MECHANISM OF PYRIN ACTIVATION Paul J Baker, Vasiliki Lagou, Isabelle Jéru, Lien Van Eyck, David A Parry, Dylan Lawless, Dominic De Nardo, Josselyn E Garcia-Perez, Laura F Dagley, Caroline Holley, James Dooley, Fiona Moghaddas, Emanuela Pasciuto, Pierre-Yves Jeandel, Raf Sciot, Dena Lyras, Andrew I Webb, Sandra E Nicholson, Lien De Somer, Erika van Nieuwenhove, Julia Ruuth-Praz, Bruno Copin, Emmanuelle Cochet, Myrna Medlej-Hashim, Andre Megarbane, Kate Schroder, Sinisa Savic, An Goris, Serge Amselem, Carine Wouters, Adrian Liston, Seth L Masters Oral presentation18.10.201616:15Grand Ballroom B/CPrimary immunodeficiencies: lessons for cytokine and interferon biologyScientific Session
O022STING-DEPENDENT CYTOKINE SIGNALING MANIFESTS SELF DNA INDUCED AUTOINFLAMMATORY DISEASE. Jeonghyun Ahn, Glen Barber Oral presentation18.10.201616:30Grand Ballroom B/CPrimary immunodeficiencies: lessons for cytokine and interferon biologyScientific Session
O022STING-DEPENDENT CYTOKINE SIGNALING MANIFESTS SELF DNA INDUCED AUTOINFLAMMATORY DISEASE. Jeonghyun Ahn, Glen Barber Oral presentation18.10.201616:45Grand Ballroom B/CPrimary immunodeficiencies: lessons for cytokine and interferon biologyScientific Session
O023IL-27 INDUCED BY SELECT CANDIDA SPP. VIA TLR7/NOD2 SIGNALING AND IFN-B PRODUCTION INHIBITS FUNGAL CLEARANCE Selinda J Orr, Emmanuel C Patin, Adam V Jones, Aiysha Thompson, Mathew Clement, Gareth W Jones Oral presentation19.10.201609:00Grand Ballroom ACytokines and orchestration of innate and adaptive immunityScientific Session
O024HOMEOSTATIC STAT5 SIGNALING DRIVES ACCUMULATION AND FUNCTION OF INNATE LYMPHOCYTES Alejandro Villarino, Giuseppe Sciumè, Gertraud Robinson, Lothar Hennighausen, John O'Shea Oral presentation19.10.201609:45Grand Ballroom ACytokines and orchestration of innate and adaptive immunityScientific Session
O025INNATE LYMPHOID CELL FUNCTION IN ALLERGIC INFLAMMATION: ARGINASE 1 IS A CRITICAL METABOLIC CHECKPOINT CONTROLLING TYPE 2 INFLAMMATION Laurel A Monticelli, Michael D Buck, Anne-Laure Flamar, Steven A Saenz, Elia D Tait Wojno, Naomi A Yudanin, Lisa C Osborne, Matthew R Hepworth, Sara V Tran, Hans-Reimer Rodewald, Hardik Shah, Justin R Cross, Joshua M Diamond, Edward Cantu, Jason D Christie, Erika L Pearce, David Artis Oral presentation19.10.201611:30Grand Ballroom AInnate lymphoid cells: first responders in immunity and inflammationScientific Session
O026REGULATION AND FUNCTION OF THE TYPE 2 IMMUNE MODULE IN ADIPOSE TISSUE Ari Benjamin Molofsky Oral presentation19.10.201612:15Grand Ballroom AInnate lymphoid cells: first responders in immunity and inflammationScientific Session
O027ELUCIDATING THE EPIGENETIC REGULATION OF CD4+ T CELL DERIVED IL-10 DURING INFLUENZA INFECTION Nicolette Fonseca, Alireza Lorzadeh, Stephen Alexander Redpath, Martin Hirst, Georgia Perona Wright Oral presentation19.10.201611:30Grand Ballroom B/CTranscriptional and epigenetic regulation of cytokine responsesScientific Session
O028IMMUNE-RESTRICTED EPIGENETIC READER SP140 MAINTAINS TRANSCRIPTIONAL PROGRAMS REQUIRED FOR MACROPHAGE IDENTITY AND INTESTINAL HOMEOSTASIS Stuti Mehta, D. Alexander Cronkite, Megha Basavappa, Cisca Wijmenga, Ramnik J Xavier, Kate L Jeffrey Oral presentation19.10.201612:15Grand Ballroom B/CTranscriptional and epigenetic regulation of cytokine responsesScientific Session
P001IFN-Λ4 HAS A POTENT ANTIPROLIFERATIVE ACTIVITY IN B-CELL LYMPHOMA AND HEPATOMA CELL LINES Adeola Obajemu, Olusegun O Onabajo, Nina Rao, Rouf Banday, Ludmila Prokunina-Olsson Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P002HCV CORE PROTEIN TRIGGERS IL-1B PRODUCTION VIA THE NLRP3 INFLAMMASOME Amina Abduletif Negash, Lauren D Aarreberg, Rebecca M Fritzemeier, Michael J Gale, Jr. Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P003REGULATION OF THE CCL2-CCR2 AXIS THROUGH THE JAK-STAT PATHWAY AND ROLE IN CANCER METASTASIS Aradhana Rani, Roseanna Greenlaw, John Murphy, Christine Galustian Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P004LOSS OF IRF5 INDUCES SPONTANEOUS MAMMARY TUMORIGENESIS Dan Li, Xiaohui Bi, Corey Goyeneche, Amy Pitler, Betsy Barnes Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P005PROTEOLYTIC ORIGIN OF THE SOLUBLE HUMAN IL-6R IN VIVO AND A DECISIVE ROLE OF N-GLYCOSYLATION Christoph Garbers, Steffen Riethmueller, Prasath Somasundaram, Johanna C. Ehlers, Tomas Koudelka, Chien-Wen Hung, Andreas Tholey, Stefan Rose-John Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P006DISTINCT ROLES FOR IRF5 IN MAMMARY EPITHELIAL CELLS AND HOST TUMOR IMMUNITY: LOSS OF IRF5 IN EITHER COMPARTMENT LEADS TO TUMORIGENESIS Dan Li, Betsy Barnes Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P007SEXUALLY DIMORPHIC ROLES OF STAT3 IN PEDIATRIC BRAIN CANCER. Christine White, Samantha Jayasekara, Jason Cain, Daniel Gough Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P008DISRUPTION OF PD-1/PD-L1 SIGNALING IN 2D VS. 3D COLORECTAL CANCER COCULTURE MODEL REVEALED BY RNAI HIGH THROUGHPUT SCREEN Daniel jake Fernandez, Jiaqi Fu, Madhu Lal Nag Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P009POLIO VIRUS THERAPY HAS IMMUNOSTIMULATORY PROPERTIES THAT ARE ACTIVE AGAINST SOLID TUMORS Eda Holl, Michael Brown, David Boczkowski, Darell Bigner, Matthias Gromeier, Smita Nair Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P010SUPPRESSOR OF CYTOKINE SIGNALING 5 LOSS PROMOTES BREAST CANCER Edmond Linossi, Laura Dagley, Tatiana Kolesnik, Marie-Liesse Asselin-Labat, Jane Visvader, Jeffrey Babon, Nic Nicola, Andrew Webb, Sandra E Nicholson Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P011P-ERK ACTIVATION THROUGH P70S6 KINASE PHOSPHORYLATION CORRELATES WITH AUTOPHAGY ON MELANOMA CELL LINES Elena Toniato, Vincenzo De Iuliis, Marika Caruso, Antonio Marino, Andrea Saggini, Claudio Talora, Vincenzo Flati, Stefano Martinotti Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P012THE ROLE OF GRANULOCYTE-COLONY STIMULATING FACTOR IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE Evelyn Tsantikos, Maverick Lau, Mhairi Maxwell, Gary Anderson, Margaret Hibbs Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P013CYTOKINE-DRIVEN LOSS OF PLASMACYTOID DENDRITIC CELL FUNCTION IN CHRONIC LYMPHOCYTIC LEUKEMIA Damien Saulep-Easton, Fabien Vincent, Melanie Le Page, Andrew Wei, Stephen Ting, Carlo Croce, Constatine Tam, Fabienne Mackay Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P014EXPLORATION OF IFNLR1-DEPENDENT AND INDEPENDENT CANCER-RELATED FUNCTIONS OF IFN-Λ4 IN A HEPATOMA CELL LINE Fang Wang, Olusegun O Onabajo, Ludmila Prokunina-Olsson Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P015INFLAMMATORY MICROENVIRONMENT AND HUMAN PAPILLOMAVIRUS-INDUCED CARCINOGENESIS Giovanna Romeo, Giorgio Mangino, Maria Vincenza Chiantore, Gianna Fiorucci, Marco Iuliano Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P016DEREGULATION OF STING SIGNALING IN COLORECTAL CARCINOMA CONSTRAINS DNA-DAMAGE RESPONSES AND CORRELATES WITH TUMORIGENESIS Hiroyasu Konno, Tianli Xia, Jeonghyun Ahn, Glen N Barber Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P016-bAPOBEC MUTAGENESIS: A NEW LINK BETWEEN INNATE IMMUNITY AND CANCER Rouf Banday, Olusegun O Onabajo, Krizia-Ivana Udquim, Mauricio Marquez-Palencia, Adeola Obajemu, Candace D Middlebrooks, Ludmila Prokunina-Olsson Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P016-dFLOW-BASED, CELL TYPE-SPECIFIC MULTIPLEX ASSAY PANELS AS USEFUL TOOLS FOR INNATE AND ADAPTIVE IMMUNITY RESEARCH Binggang Sun, Priyanka Rughwani, Shaoquan Ji, Weiping Jiang Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P016-eONCOSTATIN M INDUCES ARGINASE 1 + MACROPHAGE ACCUMULATION IN MURINE MODELS OF AIRWAY INFLAMMATION AND CANCER GROWTH, BUT ACTS INDIRECTLY THROUGH ITS INDUCTION OF IL-6 AND IL-4/IL-13 CYTOKINE SIGNALING Anisha Dubey, Ehab Ayaub, Laura Izakelian, Kyle Stephenson, Fernando Botelho, Kjetil Ask, Carl Richards Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P016-fXCL1-PRODUCING INVARIANT NKT CELLS PROMOTE ALLERGIC AIRWAY RESISTANCE BY RECRUITING CD103+ DENDRITIC CELLS Doo Hyun Chung, Yeon Duk Woo, Hye Young Kim Poster presentation17.10.201617:00 Poster viewing: Immune regulation of inflammation and cancer IPoster Session
P017LACTOBACILLUS AND BIFIDOBACTERIUM TREATMENT CONTRIBUTE TO AN IMMUNOREGULATORY PROFILE THROUGH UP REGULATION OF TGF-Β/FOXP3 IN EXPERIMENTAL COLITIS IN MICE. Ryma Toumi, Imene Soufli, Chafia Touil-boukoffa Poster presentation17.10.201617:00 Poster viewing: The microbiota and regulation of inflammationPoster Session
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